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Gajendran, N.
- The Impact of Water Pollution on the Socio-economic Status of the Stakeholders of Ennore Creek, Bay of Bengal (India): Part I
Abstract Views :357 |
PDF Views:306
Authors
V. Shanthi
1,
N. Gajendran
2
Affiliations
1 University of Madras, 1Dept. of Economics, Chellammal Women’s College, Guindy, Chennai-600 005, IN
2 University of Madras, C.A.S. in Botany, University of Madras, Chennai-25, IN
1 University of Madras, 1Dept. of Economics, Chellammal Women’s College, Guindy, Chennai-600 005, IN
2 University of Madras, C.A.S. in Botany, University of Madras, Chennai-25, IN
Source
Indian Journal of Science and Technology, Vol 2, No 3 (2009), Pagination: 66-79Abstract
No AbstractFull Text
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- Low Amount Expression of Ku 70 Protein Related to Radiation-induced Chromosome Instability and Radiosensitivity in Normal Lymphocytes, and Leukemia and Lymphoma Cell Lines
Abstract Views :743 |
PDF Views:172
Authors
Affiliations
1 Department of Radiobiology, Institute for Environmental Sciences, Rokkasho, Aomori ,039-3213, JP
2 Department of Cancer Cytogenetics, Research Institute for Environmental Sciences, Hiroshima University, Hiroshima, JP
3 Department of Plant Biology & Plant Biotechnology, Presidency College, Chennai-600 005, IN
1 Department of Radiobiology, Institute for Environmental Sciences, Rokkasho, Aomori ,039-3213, JP
2 Department of Cancer Cytogenetics, Research Institute for Environmental Sciences, Hiroshima University, Hiroshima, JP
3 Department of Plant Biology & Plant Biotechnology, Presidency College, Chennai-600 005, IN
Source
Indian Journal of Science and Technology, Vol 6, No 2 (2013), Pagination: 3981-3989Abstract
Previous our experiment showed that B-lymphoid cell lines established from α ray- and γ-ray irradiated lymphocytes had higher chromosome instabilities through many passages than that from non-irradiated lymphocytes. Present protein study revealed that these B-cell lines had low amount of Ku 70 protein expression before and after second irradiation, longer localization of Ku 70 protein in nucleus, longer period of cell cycle delay at G1 or G2 phases and high activity of DNA-PK. The first αray- or γ-ray irradiation had an effect of persisting impaired DNA repair system in cells, which resulted in a decreased repair capacity after the second irradiation. Leukemia and lymphoma cell lines also showed similar characteristics after irradiation to those of the B-cell lines having high chromosome instability. These similarities are suggesting that characteristics on abnormal Ku 70 protein might persist long term and might be related to initiating leukemogenesis and lymphomagenesis as well as that such an ability of DNA repair protein might apply to prediction of radiosensitivity of leukemia or lymphoma cells.Keywords
DNA Repair, Ku 70 Protein, Chromosome Aberration, Radiosensitivity, Radiation, Chromosome Instability, Leukemia and Malignant LymphomaFull Text
References
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- Antimicrobial Activity of Aegle Marmelos (correa) Linn. Silver Nanoparticles
Abstract Views :348 |
PDF Views:157
Authors
Affiliations
1 Deptartment of Medical Biochemistry, University of Madras, Chennai, IN
2 Department of Biochemistry JBAS College, Chennai, IN
3 CLRI, Chennai, IN
4 PNG University of Technology, PG
5 Department of Plant Biology and plant Biotechnology, Presidency College, Chennai-600 005, IN
1 Deptartment of Medical Biochemistry, University of Madras, Chennai, IN
2 Department of Biochemistry JBAS College, Chennai, IN
3 CLRI, Chennai, IN
4 PNG University of Technology, PG
5 Department of Plant Biology and plant Biotechnology, Presidency College, Chennai-600 005, IN
Source
Indian Journal of Drugs and Diseases, Vol 3, No 1 (2014), Pagination: 294-297Abstract
Objective: The present study was carried out for investigating the antibacterial activity of sliver nanoparticles (Ag NPs) biologically synthesized from the medicinal plant Aegle marmelos.
Methods: The silver nanoparticles from Aegle marmelos was impregnated onto a blank disks with different concentrations viz., 1mM, 3 mM and 5 mM and tested for its antimicrobial activity against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 25923), Pseudomonas aeuruginosa (ATCC 27853), and Candida albicans (ATCC 10231).
Results: The results indicated highest antimicrobial activity against E.coli and P. aeruginosa as a solution for finding.
Conclusion: The ability of Aegle marmelos silver nanoparticle to inhibit bacterial and fungi is an indication of its broad spectrum antimicrobial activity which could be a potential source of antibiotic which is cost effective and eco-friendly against drug resistant organisms.
Keywords
E. Coli , C. Albicans, P. Aeuruginosa , S. Aureus, Aegle Marmelos , Silver NanoparticlesFull Text
- Antimicrobial Activity of Silver Nanoparticles from Swietenia Mahagoni
Abstract Views :352 |
PDF Views:188
Authors
Affiliations
1 Department of Medical Biochemistry, University of Madras, Chennai-600113, IN
2 Department of Biochemistry JBAS College, Chennai 6000 018, IN
3 CLRI, Chennai 600020, IN
4 PNG University of Technology, PG
5 Department of Plant Biology and Plant Biotechnology, Presidency College, Chennai-600005, IN
1 Department of Medical Biochemistry, University of Madras, Chennai-600113, IN
2 Department of Biochemistry JBAS College, Chennai 6000 018, IN
3 CLRI, Chennai 600020, IN
4 PNG University of Technology, PG
5 Department of Plant Biology and Plant Biotechnology, Presidency College, Chennai-600005, IN
Source
Indian Journal of Medicine and Healthcare, Vol 3, No 1 (2014), Pagination: 310-313Abstract
Objective: To produce natural, non-toxic biologically synthesized silver nanoparticles (Ag NPs) with antimicrobial activity from plant source, Swietenia mahagoni as a remedy for multi-resistant drug microbes.
Methods: The antimicrobial activity of these Ag NPs from Swietenia mahagoni was tested against three bacterial species, E.coli, S. aureus, P. aeruginosa and a fungal species, C. albicans.
Results: The experimental results exhibited satisfactory inhibitions against all tested microorganisms when used at different concentrations viz., 1mM, 3 mM and 5 mM; 3 mM (20 mg/500 μl distilled water) offered the highest sensitivity for E.coli and P. aeruginosa.
Conclusion: Green-synthesized antibacterial agent from Swietenia mahagoni showed good antibacterial and antifungal activity.
Keywords
E. Coli, C. Albicans , P. Aeuruginosa, Pithecellobium Dulce, S. AureusFull Text
- Green Synthesis and Characterisation of Silver Nanoparticles from the Medicinal Plant Pithecellobium Dulce
Abstract Views :289 |
PDF Views:189
Authors
Affiliations
1 Dept of Biochemistry, Dept of Medical Biochemistry University of Madras, Chennai, IN
2 PNG University of Technology, PG
3 Department of Biochemistry, JBAS College, Chennai, IN
4 Tannary Department, CLRI, Adyar. Chennai, IN
5 Department of Plant Biology and Plant Biotechnology, Presidency College, Chennai-600005, IN
1 Dept of Biochemistry, Dept of Medical Biochemistry University of Madras, Chennai, IN
2 PNG University of Technology, PG
3 Department of Biochemistry, JBAS College, Chennai, IN
4 Tannary Department, CLRI, Adyar. Chennai, IN
5 Department of Plant Biology and Plant Biotechnology, Presidency College, Chennai-600005, IN
Source
Indian Journal of NanoScience, Vol 2, No 8 (2014), Pagination: 04-09Abstract
Objective: To introduce a cost effective and eco-friendly technique of preparing silver nanoparticles (Ag NP) from the medicinal plant, Pithecellobium dulce.
Methods: Ag NP of different concentration was prepared and characterized by using UV-Vis Spectrophotometer, Transmission Electron Microscopy (TEM), Scanning Electron Microscopy, X-Ray Diffraction (XRD), and Fourier Transform Infra Red (FTIR).
Results: Studies by UV-Vis spectroscopy showed absorption spectra of silver nanoparticles at an absorbance peak at 475nm, in all the three different concentrations (1mM, 3mM and 5mM). The size of Ag NP ranged 50-70nm and appeared to be dominantly spherical (and occasionally triangular). The XRD pattern revealed that these silver nanoparticles have a crystalline nature.
Conclusion: These nanoparticles produced by green synthesis proved stable in solution and can have promising role in nano-medicine.
Keywords
Pithecellobium Dulce, Bioreduction, Silver NanoparticlesFull Text